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Thus, without minimizing the improved progression-free survival associated with pharmacologic CDK4/6 inhibition in ER+ breast cancers, our data suggest that in the subset of tumors with, and potentially addicted to, cyclin D1 amplification or rearrangement, a more effective path to impactful tumor shrinkage as opposed to slowing of growth will be to develop agents that target cyclin D1 directly.
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At that end, the current methodology demonstrated a high performance in minimizing the energy loss, improving the voltage profiles and relieving the bottlenecks in the lines.
In this trade-off study, a multi-objective optimization is formulated and performed, targeting for both minimizing the drag to improve flight efficiency and reducing the gust-induced wing bending moment to enhance the structural integrity.
As minimizing the PEPs can improve the BER performance of the VBLAST detector, our target is to design a unimodular matrix such that the PEPs will be minimized.
By integrating the radio controller function, eNodeB provides the air interface with the user plane and control plane protocol terminations towards the UE, minimizing the latency and improving the efficiency.
It avoids the substitution of the old buildings with new ones, minimizing the waste and improving the long-term (indeed, in some case, a very, very long term) performance of the buildings, instead of the short time horizons involved in usual "new" projects (Bon 1999).
Minimizing the attrition rate improves the representativeness of the results.
Therefore, prewarning severe aGVHD is related to minimizing the incidence and improving the prospects of survival directly [ 9].
Future research should seek to elucidate the underlying mechanisms of HMB-FA in minimizing the negative and improving the positive effects of high-intensity training adaptations.
Numerous successful strategies have been developed for minimizing the substrate cost and improving the product yields.
Examples are included to show that minimizing the proposed performance index improves the transient response when compared to the standard quadratic performance often used in MPC.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com