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Advances in radiotherapy techniques allow targeted treatment of the disease, whilst minimizing the dose to organs at risk.
Photodynamic therapy of solid organs requires sufficient PDT dose throughout the target tissue while minimizing the dose to proximal normal structures.
An important feature of these approaches is to reach the tumor tissue while limiting or minimizing the dose to normal organs.
The plans based on superimposed CT image datasets achieved full coverage of the tumor, while allowing tight margins around the PTV and minimizing the dose to OARs.
This study was undertaken to determine the feasibility of dose escalation using proton therapy, as compared to conventional 3-dimensional conformal radiation, by minimizing the dose to normal tissues.
The best shield is minimizing the dose of radiation and limiting the time exposed as much as possible.
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A selective SNRI, such as duloxetine or milnacipran, could thus show greater overall benefit by enhancing the serotonergic and noradrenergic effects that lead to drug efficacy, while minimizing the dose-limiting effects of toxicity.
In recent years, the volumetric modulated arc therapy (VMAT) technique has been widely used to treat prostate cancer because VMAT allows the delivery of a conformal dose distribution to the PTV while minimizing the doses to nearby critical structures [2].
Present investigation was designed to study the synergistic potential of NuBCP-9 and PTX loaded polymeric nanoparticles to minimize the dose and improve the efficacy and safety.
The system has been designed to minimize the dose incurred during alignment and focusing, making it useful in both negative stain and cryo-electron microscopy.
Specifically for CBCT, leaded glasses, thyroid collars and collimation (smaller field of view (FOV) especially for paediatric patients) minimize the dose to organs outside the FOV.
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