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The practical identifiability of each law is examined by generating synthetic 3D tags from in silico simulations, allowing mapping of the objective function landscape over parameter space and comparison of minimizing parameter values with original ground truth values.
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To minimize parameter explosion across our many stimulus conditions, we tested only a single dependent measure of the BOLD response.
Note that a small λ is already sufficient to minimize parameter changes, while the experimental data is still described very well.
Though we attempted to use patient samples from matching decades of life, given the resources available, we erred to minimize parameters that would lead to degradation of RNA such as post-mortem interval and brain pH.
We therefore agree that, despite our wish to minimize parameters and avoid arbitrary cutoffs, requiring at least one (uniquely aligned, high quality) RNA read to support editing is reasonable.
In device design, a narrow emitter and reduced poly single-crystal interfacial oxide are impoly single-crystal minterfacialevice parameter shifts.
Combining observed fouling rates with measured particle size distribution and minimizing both parameters indicates a desirable sustainable aeration rate for given wastewater characteristic, operating parameters (i.e. production/backwash flux, recovery) and membrane module geometry.
Besides, better Quality of Service (QoS) could be achieved in TWIN by minimizing two parameters: queueing delay and delay variance.
Specifically, HOD selects those samples which minimize the parameter covariance matrix of the Hessian regularized regression model.
Therefore, it is natural to adopt machine learning approach into the knowledge-oriented controllers to enhance their performance and minimize tedious parameter tunings.
Algorithms such as SLIDE, NSMAP or others that explicitly enumerate the candidates and minimize the parameter in the candidate space also return one of several solutions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com