Sentence examples for minimizing immune from inspiring English sources

Recent and ongoing research, presented in this review, seeks to address the challenge of protein therapeutic immunogenicity by elucidating the mechanisms underlying immune recognition of protein therapeutics, establishing preclinical methods for assessing immunogenicity and developing strategies for minimizing immune responses.

This would indicate a feeding-like effect of cardiac ATDPCs on allogeneic T cells, promoting cell viability while minimizing immune response to alloantigens.

Given that arthropod saliva is a cocktail of molecules selected through evolution to optimize access to the blood of vertebrates and minimize immune reactions [17], [20], [28], [29], it is not surprising that anti-salivary immunity takes so long to develop under natural conditions.

We have been testing numerous design modifications of micro-dystrophin expression cassettes to increase expression, improve functionality of micro-dystrophins and minimize immune recognitions of the delivered protein.

Studies showed that SWCNT did not activate immune proteins [ 6] and modified surface of the nanotubes could minimize immune response [ 7].

However, for hESC to be used in a wide range of treatments, it is imperative to minimize immune responses following transplantation of differentiated progeny.

Given these lymphocyte responses, it is recommended that a rest day be incorporated following two consecutive days of a high-intensity intermittent run program to minimize immune cell modulations and reduce potential susceptibility.

It is also possible to create a bank of pluripotent cell lines to match the human leukocyte antigen 'cell type' and minimize immune reactions for a large percentage of the population (Nakatsuji et al., 2008).

The capital investment required to populate clinical grade hESC banks with therapeutically relevant lines is therefore significantly reduced, by pre-selecting those embryos for derivation with desirable HLA phenotypes – hence addressing both the cost of treatment and the need to minimize immune rejection upon transplantation.

It is believed that by decreasing T-cell responsiveness to TCR stimulation, p12 selectively curtails viral expression to minimize immune recognition of infected CD4+ T-cells and impair the function of infected cytotoxic CD8+ T-cells, thereby providing a favorable environment for viral persistence in the infected host.

Thus inhibition of MMP via increased expression of TIMP-1 may point to an evasive strategy by the parasite to limit access of immune cells or a host response to minimize immune-mediated pathology.