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Finally, we were able to measure individual serum TCDD concentrations near the time of exposure, thus minimizing exposure misclassification.
Minimizing exposure misclassification among the unexposed most affected the referent group in the prior analysis, but the increased risk of breast cancer remained among more highly exposed women.
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Cohort studies designed to estimate human health effects of exposures to urban pollutants require accurate determination of ambient concentrations in order to minimize exposure misclassification errors.
To minimize exposure misclassification, catchment buffer areas of 8 and 30 km were drawn around each monitor.
Our assessment should minimize exposure misclassification by capturing variation among terminals and across U.S. regions, and changes over time.
In future studies, more frequent collection of urine samples spanning all three trimesters of pregnancy may minimize exposure misclassification and better characterize gestational exposure.
A single indoor air sample may be sufficient to characterize phthalate exposure in the home, whereas urinary phthalate biomarkers should be sampled longitudinally during pregnancy to minimize exposure misclassification.
According to the results obtained in this study, some recommendations can be made to improve the assessment of the subject's exposure based on available TTHM and HAA9 data in epidemiological studies and thus to minimize exposure misclassification (Table 6).
However, the reader who was trained by Norman Boyd, an expert on MD and one of the developers of Cumulus [ 20], regularly calibrated herself against his measurements and had a high intra-observer correlation (R2 = 0.92), which should minimize exposure misclassification.
While exposure assessment may add substantial costs limiting feasibility, future health studies, which use a combination of measurements in a nested subset of health assessment households together with exposure models, are needed to minimize exposure misclassification, thereby strengthening the evidence for association while providing relevant exposure-response information.
On the other hand, if multiple urine collections are taken over a period of time, changing the time of day of collection may provide the most complete approach for exposure assessment, particularly when multiple phthalates and/or other compounds are evaluated, and thus minimize exposure misclassification.
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