Sentence examples for minimizing effects on from inspiring English sources

Furthermore combinations of drugs may allow a more targeted approach for a selection of subtypes of a disease, while minimizing effects on unaffected cells.

These data suggest that LY2784544 has potential for development as a targeted agent against JAK2V617F and may have properties that allow suppression of JAK2V617F-induced Mpathogenesissis while minimizing effects on hematopoietic progenitor cells.

Understanding drug-target interactions also opens up the possibility of combining a number of approved drugs to enhance activity against a common therapeutic target, while minimizing effects on other targets.

As a measure of the concentration required for lysing 50% human cells compared to the minimal concentration for inhibiting bacterial growth (MIC) selectivity, S, is defined by eq 3. High selectivities mean effective antimicrobial activity while minimizing effects on human cells.

In an ideal world, neural stimulation technology would effectively elicit intended activity in targeted structures while minimizing effects on non-targeted structures.

Thus, a critical feature of the final molecule is a flat exposure profile that maintains an efficacious dose while minimizing effects on baseline glucose levels.

If these observations hold true in translation to human MPN clinical testing, LY2784544 may provide a potential clinical advantage in targeting JAK2V617F-induced Mpathogenesissis while minimizing effect on normal progenitor cells in patients with a JAK2V617F MPN.

To minimize effects on sleep patterns, the AOA recommends powering down at least one hour before bedtime.

The warmed seawater would then be allowed to cool before it was pumped back into the gulf to minimize effects on the environment.

The study says that noise and odors will not be a problem, that increased traffic can be mitigated and that while dredging will disturb silt in the bay "to some degree," the department will take "appropriate measures" to minimize effects on water quality.

This risk is actually an unintended consequence of the need for new products to have minimal "non-target" effects on biological organisms other than fungi: the biochemical focus on a single aspect of fungal metabolism, which minimizes effects on other life forms, also means that fungal individuals don't need to change their metabolism very much in order to avoid the fungicide's activity.