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Its once-daily dosage form is potentially good for improving compliance of older adults and for minimizing dosing errors.
While co-formulated therapies can be beneficial for minimizing dosing errors and improving medication adherence through a reduced pill burden, caution should be exercised among older individuals.
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Background: Radiotherapy is based on the premise of accurate dose delivery to target volumes within a patient, while minimizing dose to surrounding tissues.
This modality circumvents the technical limitations of relying on multiple en face electron fields while minimizing dose to adjacent normal tissues.
During the dose optimization process the dose constraints were adjusted to obtain adequate and homogeneous target volume coverage while minimizing dose in heart, spinal cord, and both lungs.
Protons have also been used in the treatment of prostate cancer to achieve dose escalation while minimizing doses to normal tissues [ 23].
Radiotherapy treatment planning is, in broad terms, the process of planning the delivery of a prescribed dose to a tumor or target volume while minimizing dose to the surrounding critical structures.
Treatment planning typically involves delivering an adequate dose to the intact breast while minimizing doses to the critical lung, heart, and contralateral breast organs using the conventional tangential field technique.
Thus, a single administration of MSCs-IFN β could offer significant advantages over protein delivery by requiring less frequent injections and long-term expression of protein, resulting in therapeutic efficacy, while minimizing dose-limiting side effects.
A maintenance period followed at which 20 mA was applied until the next feeding event as to minimize dosing of acidified extractant into the broth.
Systems can be designed to involve minimal operator intervention, to minimize dose to the sample, and to provide high throughput at commercial seaports, airports and other entry points.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com