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Such a modeling approach that is capable of an independent investigation of the influence of various parameters on spray retention can be used to improve understanding of application methods and adjuvants that could help minimizing development of resistance in problematic weed species.
Finally, minimizing development of compensatory mutations would involve early discontinuation of PI therapy when antiviral therapy is unlikely to succeed.
Proper public knowledge and attitude toward antibiotics is an important factor in rational antibiotic use and therefore minimizing development of antibiotic resistance [ 29].
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Antibiotics are widely-used medicines for which a more prudent use has been advocated to minimize development of resistance.
To ensure optimal effectiveness of antivirals and to minimize development of drug resistant viral strains, the use of antivirals for annual influenza should be restrictive.
This is likely to be particularly of concern regarding therapeutics, such as ACTs and antimicrobials which rely on appropriate usage to minimize development of resistance (WHO 2002, 2010a).
7 Additionally, alternating cycles have been favored historically as an effort to minimize development of tobramycin resistance, namely bacterial impermeability, with chronic therapy.
We cultured both species for two days on plates, compared to five-days used for the initial H. pylori proteome analysis [ 87], to minimize development of coccoid forms [ 88].
This dilemma has motivated researchers to seek a structured process for selecting the most promising design, one that will realize the benefits of transferability while minimizing development costs.
Inhibition of IMPDH significantly increased the sensitivity of the resistant cell lines to MTX, indicating that targeting IMPDH might constitute a promising means of minimizing the development of resistance [20], [21].
First, there is the hope of minimizing the development of resistance against major P. aeruginosa active substances.
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