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Using RNPs is compatible with co-CRISPR (Paix et al. 2015), which further boosts editing efficiency and minimizes screening.
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Further investigations are needed not only to establish a solid understanding of preschoolers' habitual screen-viewing behaviors while in childcare, but to modify the childcare environment (and the policies/curriculum therein) in a way that best minimizes screen-related activities during childcare hours as well.
Improvement of the assay using different co-treatments (besides 5-aza-2′-dC) to increase rates of XCR, may lead to identification of different classes of Xi maintenance factors and minimize screening false negatives and positives [ 43].
A structure-guided "semirational" method for library creation allows researchers to target specific amino acid positions for mutagenesis, concentrating mutations where they might be most effective in order to produce mutant libraries of a manageable size, minimizing screening effort while maximizing the chances of finding improved mutants.
To minimize screening costs, we initially selected 48 of 117 pairs following criteria detailed in Lepais and Bacles (2011).
These findings will likely be applicable for a range of genome editing approaches in C. elegans, which will improve editing efficiency and minimize screening efforts.
18 Lastly, to minimize screening bias, we conducted sensitivity analyses accounting for frequency of patient visits and/or contact with the healthcare system as well as frequency of serum creatinine screening.
The recent advances in NGS technologies have ensured that sequencing has become a more accessible avenue that may permit a rational approach to reduce the number of potential candidates for such trials, and to minimize screening times and labour-intensive culture techniques.
At that point it also came out of stealth to discuss its first products: a range of high end wearable jewelry, in premium materials such as sterling silver and gold plating, that were designed to help people minimize screen-based distractions by routing select notifications as buzzes on wrists, fingers or collar bones.
Nevertheless, it is important to note that the presence of screen-use policies in childcare was highlighted in over half of the studies in this review that spoke to the availability screen-viewing in childcare; [ 48, 52, 54, 56, 59] therefore suggesting that, in many instances, mechanisms are in place to help minimize screen-viewing in childcare.
It generates 2 pixels per mirror by optically shifting the image back and forth rapidly on the screen, a new does-it-with-mirrors trick that on initial viewing appears to minimize the already minimal screen-door effect at the expense of overall sharpness.
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