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This non-linear warping technique minimizes between-subject structural variations.
The internal size standard ensures proper alignment of heteroduplex peaks and minimizes between-run variation.
Year-to-year consistency of results also minimizes between-year bias and suggests that differences in contaminant levels between 2008 and 2009 samples of the same product are true differences.
In addition, this meta-analysis was based on individual patient data from a consistently designed, large clinical development programme; this allows consistent derivation of endpoints and extensive subgroup analyses and minimizes between-study heterogeneity that can confound analyses of unrelated studies.
Clusters are often taken from preexisting units, but may be formed to minimize between-cluster variance, or to equalize exposure to a treatment or risk factor.
Prior to any treatment, groups were constituted so as to minimize between-group variability by using the following criteria.
Therefore, in order to minimize between-centre variability, we transformed the data in to z-scores prior to our statistical analyses.
The comparisons are all within-journal, to minimize between-journal differences in content, quality and average citation levels ("journal impact factor"); OA articles are keyword-matched to their non-OA controls in order to minimize any differences still further.
All samples were assayed in two batches to minimize between-run analytic variations.
Randomization to delivery formats will occur by YMCA location to minimize between-group contacts.
A practical solution is to apply normalization techniques prior to the statistical analysis to minimize between-plate variation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com