JCVI-syn3.0, a genomically minimized version of JCVI-syn1.0, was produced using a combination of whole-genome design (selecting DNA and organizing it in such a way as to generate a functioning genome) and chemical synthesis.
Thalberg introduced elements into their comedy designed to increase their commercial appeal: the Marx Brothers' characters were still recognizable, but Thalberg set them firmly in the real world and minimized surreal elements, while turning Groucho, Harpo, and Chico into semi-sympathetic, somewhat heroic characters.
If trust is warranted in these senses, then the danger of it is either minimized, as with justified trust, or eliminated altogether, as with well-grounded trust.
They settle on the idea that unmotivated actions are to be minimized, where an action ("actions" construed generally enough to include any change) can be motivated directly, e.g. by an axiom, or indirectly, through chains of motivations.
The most plausible and defensible version of the principle of double effect requires that the harmful side effect be minimized, so the principle of double effect provides no justification for withholding hydration and nutrition in cases in which death is not immediately imminent.
But this is not inconsistent with also respecting the person's dignity and viewing her as an end-in-herself provided that we take seriously the person's rational agency by requiring her valid consent for the organ removal and by ensuring that any risk of harm is minimized and reasonable.
As a consequence, variability in these features was not minimized and remains salient in the context of experimental observations of development.
The administrative, electoral and legislative details of this project occupied much of the last decade of his life, with its core ideas discussed in the pages of a variety of works in addition to the Code, such as Securities Against Misrule, First Principles Preparatory to Constitutional Code, and Official Aptitude Maximized; Expense Minimized.
These essays attacked waste and corruption in government and were later reissued, with other previously published essays, in Official Aptitude Maximized, Expense Minimized (1830), the overall aim of which was to optimize the competence of public servants while reducing government expenditure.
In the course of this minimization, a set of parameters (including, of course, the predicates to be minimized) is allowed to vary; the rest are held constant.
"That," the official continued, "is why the statute requires that there be minimization procedures to ensure that when communications of, or concerning, US persons are acquired in the course of lawful collection under Section 702, that information is minimized and is retained and disseminated only when appropriate.
