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Considering that the search space was expanded greatly, and the normal FDR value such as 0.01 may not be suitable, we minimized this value to 10-6 [ 8].
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The aim is to minimize this value.
The objective function is the squared difference between the simulated data (y) and the experimental data (y ∼ ) and our goal is to minimize this value for every experiment, observed species (o) and sampling point (s).
At the i-th step of the outer loop, the TRR on all but the i-th spectrum is estimated using 5-fold CV and the hyperparameters minimizing this value are selected.
A tanglegram Z=(N1,𝒳1,τ1,π1, N2,𝒳2,τ2,π2, M) is called optimal if the crossings between connectors in M is minimized by τ1 and τ2 and, among the tanglegrams minimizing this value, it can be drawn so as to minimize the sum of reticulation crossing numbers for N1 and N2.
In a forthcoming paper (Scornavacca and Huson, 2011), we will describe a heuristic for minimizing this value and a method for computing a concrete drawing of the optimized tanglegram that tries to minimize the crossing involving reticulation edges (as implemented in Dendroscope 3).
An optimal system configuration (mathbb {C}) is defined as one that minimizes this value.
He minimized the value of the motor-vehicle and criminal records Mr. Arneson gave him.
For Camus, following this reading of Nietzsche closely, the conventional solution is in fact the problem: hope is disastrous for humans inasmuch as it leads them to minimize the value of this life except as preparation for a life beyond.
This is equivalent to minimizing the value of error variance (ε 2 ).
To deal with this instability, we apply regularization techniques to minimize the value of the factor (frac{1}{mu_{n}}) for large n.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com