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A basic understanding of disease mechanisms is a prerequisite for finding effective therapy with minimized side effects.
Because NPs have the affinity to acidic environment, which characterized tumor tissue, it is believed that selective targeting strategies with NPs facilitate more effective cancer detection and treatment with minimized side effects to normal cells [1].
Our novel strategy would have profound implications in both enhanced chemotherapy efficacy and minimized side effects.
In this study, we developed pH and redox-responsive crosslinked polypeptide-based combination micelles for enhanced chemotherapeutic efficacy and minimized side effects.
Mechanistic understanding of the interaction between cavitation events and cells and tissues, as well as the subsequent cellular and molecular responses will lead to new design strategies with improved efficacy and minimized side effects.
When carbon/hydrogen isotope is used to selectively engineer some properties (e.g., thermal transport and kinetic stability), such isotopic independence of the Invar and Elinvar properties can guarantee the minimized side effects on structure and stiffness.
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Still researching is going on to find out the more effective herbal drug to cure the diabetes and reduced the free radical formation with minimized side effect.
Targeted cell delivery to lesion sites via minimally invasive approach remains an unmet need in regenerative medicine to endow satisfactory therapeutic efficacy and minimized side-effects.
Compared to conventional form of dosage, micro- and nanomaterial-based drug delivery systems have many advantages, such as reduced release rate, minimized harmful side effects and improved therapeutic efficiency [7, 14, 15].
As such, minimized bioactive side effects are achieved during the delivery process of agents.
Furthermore, the peritumoral injection of chemo-radiation therapeutic agents-encapsulated MHg formulation on tumor-bearing nude mice resulted in the desired combined treatment effect, which significantly improved the tumor growth inhibition efficiency with minimized drug-associated side effects to major organs.
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CEO of Professional Science Editing for Scientists @ prosciediting.com