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Furthermore, the decision not to allocate study personnel for bedside annotations has minimized effects of the study set-up (per se) on the nurses' decisions.
Although we minimized effects of developmental delay by assessing pups at an early time-point (P4), we found significantly reduced weight (Fig. 1) and significantly lower SPLs of DCs and USDs in homozygotes compared with heterozygotes and wild-types (Fig. 10).
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This minimized effects on females of any age-dependent decline in male reproductive performance.
The failure of ribavirin to prevent death in mice lacking type I IFN-α receptors (serum viral load was reduced, only delaying death), its poor ability to cross the blood brain barrier, and its delayed initiation in this soldier, suggest a minimized effect of ribavirin against CCHF virus in this fatal case (3, 40 ).
"This minimized the effects of any further currency fluctuation".
The fed-batch SSF offers several advantages including less water consumption, lower production cost through the reduced number and size of required equipment and utility as well as minimized negative effects of inhibitors present in lignocellulosic hydrolysate (Olofsson et al. 2008; Mohagheghi and Schell 2010; Koppram et al. 2014).
Taken together, these systematic observations offer strong support for the hypothesis that natural selection for maximized metabolic benefits and minimized side effects of the uncontrolled PAH intermediates has restricted the evolutionary trajectories of mycobacterial PAH metabolism.
However, our small study area reduced the effect of some methodological artifacts in models of larger areas for example, equivalence of the definition of land use variables in different areas and minimized potential differential effects of regional background pollution levels that were observed in other model-transferability studies (e.g., the ESCAPE study in Europe).
Under strong natural selection towards minimized side effects, impacts of the epistatic interaction of the genetic sources might restrict the possible evolutionary trajectories for mycobacteria to be able to obtain the PAH metabolic ability.
In the setting of personalized medicine, the exact molecular background of disease in a single patient could be assessed, upon which an individualized treatment regimen could be designed with maximized therapeutic effect and minimized adverse effects.
This indicates that 1 or 2 mg vit.E/kg diet of fish minimized the toxic effect of copperoxychloride.
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