Sentence examples for minimize toxic side from inspiring English sources

Understanding the molecular events that contribute to survival of and drug-induced apoptosis in hematopoietic stem and progenitor cells (HSC/P) can have impact on more rational approaches to blood cancer therapeutic design, as well as on strategies to minimize toxic side effects of chemotherapeutic drugs.

Such regimen would minimize toxic side effects by reducing drug exposure, at the same time allowing sustained upregulation of frataxin protein.

The combination of the two modalities may minimize toxic side effects [ 70, 74].

These characteristics potentially minimize toxic side effects exerted by pharmacological inhibition of the cellular targets.

Chronotherapy and chronopharmacology are currently utilized in cancer treatments, aiming to minimize toxic side effects while maintaining effective treatment.

"We wanted a drug that inhibits a protein that is only expressed in cancer cells, not in normal cells, in part because we believed this would minimize toxic side effects".

These combinations are characterized by lower doses, which minimize toxic side-effects and the emergence of multi-drug resistant mutants.

The rationale in developing such nanoparticles is to maximize drug efficacy while minimizing toxic side effects.

This can be achieved by developing combination strategies based on virus and other anticancer agents that increase cancer cell killing while minimizing toxic side effects.

Like the origin of PAH-MN discussed above, the same strength of natural selection minimizing toxic side effects might also have restricted the abandonment trajectories in the evolutionary process for disuse of the dispensable metabolic capability in the host-dependent mycobacteria.

Our results suggest that deferral of HAART favors HIV specific cytotoxic T lymphocytes while minimizing toxic side-effects, when compared to very early therapeutic intervention.