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In this mini-review we elaborate upon the rationale and design strategies for creating Dicer substrate RNAs that provide enhanced knockdown of targeted RNAs and minimize the utilization of the sense strand as RNAi effectors.
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They involve the identification of part families and machine cells so that intercellular movement is minimized and the utilization of the machines within a cell is maximized.
To overcome this difficulty, the R&D community proposed a stepped solar still in an attempt to increase the production per unit area by decreasing the thermal inertia of the water mass, where the area of the basin is minimized via the utilization of small trays.
This possibility is also minimized by the utilization of polyA tails for RNA selection and reverse transcription priming using oligo dT).
(326) Careful design of both instruments and probes can also maximize the utilization of photons, minimizing photodamage.
The objectives are to maximize the utilization of the operating rooms, minimize the overtime cost in the operating theatre, and minimize the unexpected idle time between surgical cases.
One of the strategies designed to improve this situation is the use of critical pathways, which consist of an optimal sequence guided by time of interventions performed by members of the health team for a particular procedure or diagnosis, in order to minimize delays, improve the utilization of resources and maximize the quality of health care.
Hans et al. describe optimization models for surgery planning: their approach tries to maximize the capacity utilization, minimize the risk of overtime, and minimize the number of canceled admissions [ 22, 31].
The minimize utilization of dc active power makes the slowest discharge of capacitor rate among three compensation methods, so the compensation time can be infinitely prolonged.
Therefore, our algorithms are designed in a way that minimize the number of VMs by maximizing the utilization of already initiated VMs.
We show a significant increase in the cell's usable energy density by minimizing voltage losses and maximizing the utilization of active materials in a large cell.
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