Because this age offset is thought to be relative to the sedimentation rate (Suganuma et al. 2010), geomagnetic records with higher sedimentation rates should minimize the age offset that can occur due to the PDRM lock-in process.
32, 34, 38 Therefore, muscle strengthening intervention may provide improved QoL and thus motivate the elderly to continue exercises that could minimize the age-related decline of fitness.
Although age was not significantly different between our groups and we had included age as a covariate to avoid any possible influence, it would be better to increase the sample size and minimize the age range in the future investigations.
Therefore, all the consequent measurements were carried out following the same procedure, in order to minimize the aging-related fluctuations in the SERS intensity.
Since age adjustments could not be made, analysis was carried out for specific age intervals to minimize the effect age structure might have had on cause of death (see Method section).
Moreover, the relatively young age (less than 55 years) of our patients, contributed to minimize the effects of aging on cardiac performance.
Of the 2,435 subjects, we limited the subjects to 1,332 men, aged 25 60 years, who were expected to have minimal bone turnover, to minimize the effects of age, sex, and other factors on serum osteocalcin levels.
We included patients aged < 50 years to minimize the effects of age-dependent WMHs.
Age also plays a role in immune responses and to minimize the effects of age all participants enrolled were under the age of 55.
Second, although we limited the subjects to middle-aged men to minimize the effects of age, sex, and altered bone turnover on serum osteocalcin levels, we could not entirely exclude the effects of age, sex, and other variables in the associations between plasma osteocalcin levels and glucose metabolism.
Accordingly, we used an HI-6 concentration that is at least 100-fold higher than its KD (∼100 µM) for HI-6sarinnonaged-mAChE to avoid the diffusion problem, and ran a time-course experiment to find the shortest HI-6-exposure time that can minimize the unwanted reactivation and aging and still yield a good-quality electron density map.
