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In an 18-6 vote, a panel of Food and Drug Administration experts recommended allowing the experimental drug, flibanserin, to be sold in the U.S. as long as certain safety precautions are taken to minimize potential side effects, which include low blood pressure, dizziness and fainting.
We conclude that the efficacy of combined treatment with lower doses of each drug may minimize potential side effects of treatment with these compounds.
In a double-blind design, pills were distributed and subjects were instructed to take metformin or placebo with food to minimize potential side effects.
24 As we had limited data on OXN safety/tolerability and proper titration, we initiated OXN-PR cautiously and preferred to "start slow, go slow" in order to minimize potential side effects and thereby improve the compliance to opioid treatment in our fragile population.
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A 3.5 mg nicotine patch (ie, 7 mg patch cut in half) was used to minimize potential side-effects in nonsmokers.
A primary concern in clinical trials is minimizing potential side effects that could keep the drug off the market.
When used in low to moderate doses between 38 to 400 mg caffeine daily, Soldiers and military units can take advantage of the positive operationally pertinent effects of caffeine while minimizing potential side effects such as dehydration or insomnia.
Results from the ongoing clinical trials with B-cell targeted biologics spanning a wide array of mechanisms will greatly increase our understanding of autoimmune diseases and will provide the basis for optimally matching the therapeutic approach to a given patient population to improve clinical efficacy while minimizing potential side effects.
Patients were started on an initial dose of 0.6 mg once daily for two weeks to assess tolerability of the drug and to minimize potential gastrointestinal side-effects.
Minimizing potential side effects of host modifying agents, especially in HIV/TB co-infection or when used as adjunct therapy.
The PEI-incorporated cationic liposomes system, thus, has the potential to enhance the concentrations of therapeutic payloads at the tumor site, minimize possible side effects, and ultimately increase the therapeutic index of therapies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com