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To minimize genetic variation, most of the fish in this part of the study were the offspring of random incrosses from 10 12 wild type AB parents.
The sows were artificially inseminated by the same boar to minimize genetic variation among the offspring.
98 Certain epigenetic studies compare those with T1D to healthy controls, whereas others examine monozygotic twins who are discordant for T1D to minimize genetic variation.
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To minimize genetic variations in two groups, all participants were from the same geographic regions and ethnic group.
By using variants of the same cell line, we have minimized genetic variation.
This culture was initially stocked with a single Brachionus clone, minimizing genetic variation within our Brachionus populations and reducing the potential for coevolution between predator and prey.
By analyzing half-sib baboons discordant for the quantitative trait (< 2 S.D. difference), we minimized genetic variation due to genetic background and increased the likelihood that we would discover miRNAs that are diet responsive and that differ by LDL-C phenotype.
Because the Carf mice are on a mixed C57BL6/129SvJ background, WT and KO siblings were crossed (WTxWT and KOxKO) to generate the pups for this experiment in order to minimize genetic background variations.
Only field sites where research on spider monkeys of the species A. geoffroyi was carried out were considered in our study, in order to minimize genetic influences on any behavioral variations observed.
Some strains have been maintained to preserve allelic variation, others to intentionally minimize genetic diversity, to facilitate genetic mapping and genome editing, and to control genetic background effects on mutant and other phenotypes (Haffter et al., 1996; Rauch et al., 1997; Trevarrow and Robison, 2004; LaFave et al., 2014).
All strains were backcrossed multiple times to our laboratory N2 strain to minimize other genetic variation.
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