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To minimize clonal variations, at least three clones per orientation were studied.
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It is conceivable that an adjuvant AID inhibition (i.e. AID inhibition in addition to the respective targeted cancer therapy) may minimize clonal evolution of cancer (Fig. 1).
Three differently colored labels on the Croteaux merlots signify that the wines show varying attributes caused by clonal variations in the merlot grapevines.
In the past, those dynamics are considered to be inherently Darwinian in character in which clonal destruction inadvertently enables selection pressure for the expansion of treatment- resistant clonal variations.
Two positive clones of each mutant were selected to rule out clonal variations.
The clonal variations we saw for the SAF1 family appear to support this notion.
Quite early in the history of MCF-7 cells reports on clonal variations were made in the literature.
We used the pooled clones for experiments to eliminate possible effects of individual clonal variations on the results.
cDNAs were prepared using total RNAs isolated from pools of cambium tissue and immature leaves of three trees in a clonal plantation to minimize possible individual variations.
To minimize experimental variations, the same numbers of plants were grown on the same tray.
Clonal variation in biomass distribution patterns helped explain variation in growth efficiency between the narrow crown clone (ARB-1) and wide crown clone (ARB-4).
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