Based on these observations, we hypothesize that the design of a solid dosage form with a much faster disintegration would prevent or at least minimize any deleterious gelation effects of P 188 on the ABZ dissolution rate.
The logic behind surgical resection of peritoneal disease would be to minimize any deleterious effects that peritoneal implants or their secretory products might have on oocyte quality, embryo development, or implantation.
There is likely to be a delicate balance in controlling endosymbiont proliferation within a cell so that the host can receive benefits from the endosymbiont but minimize any deleterious effects (Chrostek et al. 2013).
For this study, we developed a method for producing purified ILVs and IDLVs at high titers in order to minimize any deleterious effects upon transduction of target cells [ 20].
Although this excision leaves a 34-bp insertion, it is often placed within intronic sequences to minimize any deleterious effect to coding regions (Dickinson et al. 2015; Norris et al. 2015).
