To minimize a possible effect of the test sequence, such as a possible effect of fatigue on plantar pressures, an equal number of steps from both sessions were used for evaluation.
The test sites were measured in a random fashion in order to minimize a learning effect.
We studied early HNP1-3 appearance within 24 hours to minimize a possible effect by necrosis or apoptosis of these cells.
We tried to minimize a Hawthorne effect; that is, a change in attitude in response to attention from the investigators (15).
The observation study was conducted during a 6-week period, because prolonged observation time was expected to minimize a Hawthorne effect among the doctors.
To minimize a possible effect of CYP2D6 allele variation and to keep a homogenous group, this association was also examined among patients homozygous for the CYP2D6 Wt allele (R = 0.386, p = 0.025).
In one subject, we had to record spontaneous song after recording reactive song and to minimize a potential effect of the playback experiment, we waited for 7 days before recording spontaneous song.
To minimize a differential effect between groups, we balanced the two study arms regarding the amount of exposure to research staff, and we refer all subjects in both arms to HCV support groups.
