To minimize a bias in rating scales responses (response acquiescence bias); the survey included a mixture of positively and negatively stated items [ 18].
The probes avoided repetitive elements listed in the REPBASE database (http://www.girinst.org/repbase/index.html) and avoided SNPs present in dbSNP (release 123), the latter of which should minimize a bias due to polymorphisms in restriction enzyme sites.
Furthermore, the multi-topic survey contributed at least partly to the required "blinding" of the topic and helped to minimize a recall bias [46].
Therefore because the number of patients included in the study is low and our results need to be validated to minimize a selection bias.
All study therapists are pair-randomized to the treatment conditions (IG and CG) to minimize a possible bias.
Even if it is a subjective tool to measure adherence to ART, we had used it in a short period to minimize a recall bias which could occur.
In our present study, consecutive patients were included in order to minimize a possible bias for recruitment of patients with a history of SpA or AS, and a large number of relatives were also assessed.
One of its strengths is that it has used adequate sample size with initial random selection of the study participants from KDS -HRC data base by using a sampling frame to minimize a selection bias.
The data were collected using a standard protocol to ensure the comparability of data, the same equipment were used to measure weight, height, waist and hip circumferences, and blood pressure to minimize a possible bias in the measurements.
The patient questionnaire and information leaflet were carefully constructed to avoid an impression that not picking up the prescription would be the preferred solution, so as to minimize a desirability bias.
