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This geometry was then optimized by minimizing the energy in the same way as the initial energy minimization was carried out.
A final minimization was carried out in 8000 steps.
The energy minimization was carried out by running a customized code on a high performance computation cluster.
Energy minimization was carried out using the MOPAC module of MOE at the AM1 level of theory using a minimization gradient of 0.001 kcal/mol.
Energy minimization was carried out for all compounds using CHARMm force field to make stable conformation of protein with an energy gradient of 0.01 kcal/mol/A°.
In order to avoid adapting parameters to each of the test signals and masks, this minimization was carried out only once and only for a mixture not used in testing.
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The power minimization is carried out using voltage scaling technique, while reliability improvement is achieved through careful choice of application task mapping on the homogeneous MPSoC processing cores.
The minimization is carried out subject to constraints on the open loop control force as well as on the closed loop force.
Such a minimization is carried over all geometric mixtures of the two, healthy and damaged, elastic phases, respecting an irreversibility constraint.
A cross-flow heat exchanger matrix sizing study for matrix weight minimization is carried out, and the results show the high dependency of the potential improvements on the given operating conditions and design requirements.
The minimization is carried out using the SIMPLEX numerical optimization method running in MATLAB [32].
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