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It is shown that the minimization of the average amount of synchronization loss, and the minimization of the variability of the duration of synchronization loss occurrences, are two competing objectives; the minimization of variability is desirable because it can lead to the concealment of discontinuities.
Therefore, although a multivariate approach is likely to dramatically improve the accuracy of decision making, it will require minimization of variability in AMH assay, laboratory performance, patient population definition, and study design.
A crucial step that allows multicenter data to be combined and enables technical reproducibility of results between laboratories is the optimization of sample quality and minimization of variability due to nonbiologic (artefactual) processes.
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Indeed, the characteristic bell-shaped velocity profiles and rectilinear trajectories of horizontal reaching movements [8] [10] were simulated robustly and with varied dynamic loads, through minimization of endpoint variability alone [11].
The minimization of the variability of the maps across space, that is, a preference for smooth maps.
Minimization of glycemic variability is therefore suggested as a new target of glycemic control, which may require very frequent or almost continuous monitoring of glucose levels.
The functional is defined based on the hypothesis that the activity of the units reflects only two simple constraints: The minimization of the variability of the maps across space, that is, a preference for smooth maps.
Benefits include improved reliability, minimization of intra-rater variability and a reduction in assessment time.
Therefore, an automated sleep staging program that can fully substitute manual scoring requires minimization of subjectiveness due to inter- and inner-rater differences and maximization of robustness against many sources of variability inherited in EEG/EMG data.
The proposed background activity assessment using a (guided) crescent-shaped VOI allows minimization of both intra- and inter-reader variability and might facilitate comprehensive methodological standardization of amino acid PET which is of interest in the light of the anticipated EANM technical guidelines.
The roles of acetyl-CoA and NADPH in the regulation of PUFA biosynthesis were probed, and important genes and reactions were systematically analyzed using FBA, flux variability analysis (FVA), and minimization of metabolic adjustment (MOMA).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com