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Minimization was performed using the Minim software with a 1 1 allocation ratio and equal weighting for the three minimization factors.
Minimization factors had equal weight in the minimization algorithm.
The model adjusts for baseline variable and minimization factors.
The minimization factors (age, sex, and cause of entry to ICU) must be included as covariates in the analysis for valid estimation of the intervention effect.
The treatment effect will be adjusted for minimization factors and other covariates of interest (gender, volume/type of contrast, peri-procedural hypotension and intra-arterial balloon pump use).
A binary logistic regression will model the relative odds of receiving an unnecessary angiogram for CMR-guided care vs the group of interest (either NICE or SPECT-guided care pathways) when controlling for the minimization factors.
Similar(50)
Specialized randomization software was used to allocate patients centrally, with stratification by study site and APACHE-II classification as a minimization factor [ 8].
In fact, these samples maintain a sufficient degree of molecular mobility to afford an efficient minimization of factors that affect NMR measurements of solid materials.
Manual model building and refinement were performed using COOT (Emsley and Cowtan, 2004) and PHENIX (Adams et al., 2010) following rigid body refinement, energy minimization, B-factor refinement, and group NCS constraints.
The refinement process included successive rounds of simulated annealing, minimization, B-factor refinement, calculation of composite omit maps, difference Fourier maps, and model building.
In the latter case no adjustment will be made for the minimization or prognostic factors.
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