It served as an alternative to conventional antegrade pyelography and minimised potential risks to the foetus.
This focus also minimised potential misclassification bias due to miss rates at colonoscopy, which may be site specific, but which have been shown to be generally low for advanced neoplasia (van Rijn et al, 2006; Heresbach et al, 2008).
It is possible that the residual confounding effects of socioeconomic position or area-level deprivation may have masked or minimised potential ethnic density effects.
Although this minimised potential variation because of gender, it also means that candidate proteins, elevated in females only, will have been overlooked.
The co-culturing of the two isogenic cell lines supplied a highly important internal control and created an 'even growth environment' that minimised potential differences in cell density.
15 Since all disease episodes occurring in a defined population at risk are included in this type of study, the potential for selection bias is minimised and calculation of unbiased incidence and mortality rates seems possible.
The potential for recall or selection bias is greatly minimised, if not eliminated, due to the prospective study design.
As a small to moderate increase in risk for subgroups of heavy users or after even longer induction periods than 10-15 years cannot be ruled out, however, further studies with large study populations, where the potential for misclassification of exposure and selection bias is minimised, are warranted.
The experimental design adopted here minimised changes in relative abundance of each species with time, but did not remove the potential for sampling effects through differences in metabolic rates among species, as substrates were utilised and end-products accumulated.
Results show the potential for a continuous process for hydrogen generation from heavy hydrocarbons using sub and supercritical water with minimised carbon formation.
