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For any sequence, artefacts can be minimised by using a small field of view, high-resolution matrix, and thin sections (Fig. 1).
Because the terminal electron transfer to or from the electrode determines the overall cell potential, potential (voltage) losses can be minimised by using a mediator that has a reaction potential near that of the biological component.
In each case, crosstalk is generated, however new results are presented that demonstrate that crosstalk in a fibre parametric amplifier is minimised by using a design with the highest possible pump power and a short fibre with low nonlinearity.
Due to the symmetry of cyclic DTPA anhydride 1, the di-addition product 3 may form, which is minimised by using a large excess of cyclic DTPA anhydride 1 compared to amine 2. The reaction conditions were optimised for maximising the yield of target linker 4 by modifying a variety of parameters such as concentration and amounts of reactants.
Bias was minimised by using a similar start time and ensuring that all observers were familiar with the study protocol.
This was minimised by using a questionnaire, which used a 5 point scale and included negatively phrased questions [ 6, 16, 24].
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Recall bias regarding injurious falls was minimised by using register data.
The edge effects are minimised by using an appropriate design of the substrates so that experimental results give reliable data.
It is shown that profile power is minimised by using an untwisted elliptical planform whereas induced power is minimised by a more highly tapered planform similar to that of a hummingbird.
The use of primates was minimised by using an experimental design that permits statistically-significant changes to be demonstrated with the smallest number of animals per group and the smallest number of groups, consistent with scientific rigour.
There was a possibility of recall bias, which we tried to minimise by using a two weeks recall period.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com