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The issue of barrier penetration was minimised because the molecular target was de facto intravascular.
This limitation is minimised because the TKR population in the NJR was similar to the patient demographics from the included studies.
Selective attrition may have been minimised because the web portal also contained a forum, information and an online survey, so this also attracted participants that did not seek professional help, in contrast to interview studies among (self) referred patients.
40 42 It is possible that this risk factor is minimised because the two sexes train similarly and follow the same prevention programmes, which is uncommon in other sports.
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Incomplete follow-up was minimised because, as well as having frequent contacts, the cohort has been flagged through NHSCR since 1971, losses before than being essentially due to non-breast cancer deaths and emigrations at young ages.
As the heat conduction in the thermocouples was minimised because of the use of mineral-insulated materials a minor influence on the heat distribution during the laser heating experiment is expected because of the presence of the thermocouples.
One of the main misconceptions is that the risks of tobacco are minimised because it is purified as it passes through the water.
However, we feel that this bias was minimised because we obtained data from the head nurse who usually keeps records of all organisational details.
Bias due to loss of follow-up was minimised because mortality status was ascertained annually for all the patients in the registry.
Missing data will be minimised because patients will be visited at home for completing the questionnaires and the researcher will check if all the questions have been answered.
The modulus of elasticity of concrete were all minimised with the use of the different types of fibres.
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