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This experiment was conducted at the group level to minimise the variability due to size-dependent differences in the feeding rate.
This procedure enabled us to minimise the variability within each case-control pair, and yielded cases and controls residing in the same neighborhood of the city.
Additionally, it is important to optimise the injection protocol in patients with an implanted central venous line to minimise the variability observed with hand injections [ 20].
Clinical trial protocols are often designed to structure the delivery of care, altering the context in which an intervention is delivered to minimise the variability in ancillary care characteristics.
The nucleic acid extraction will be performed automatically (QIAcube system; QIAGEN, Hilden, Germany) to minimise the variability due to manual handling using QIAamp DNA Blood Mini Kit and RNeasyPlus Mini Kit (QIAGEN, Hilden, Germany) for DNA and RNA extraction, respectively.
These are that the RIN is above 8 (which can be considered perfect total RNA for downstream applications [ 22]) which was confirmed using the Agilent 2100 Bioanalyzer in our study, and the use of small amplicons which minimise the variability caused by RNA degradation.
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We minimised the variability and error in data interpretation by evaluating IC50 values in each experiment for individual modalities and evaluating potential synergy using the well-recognized Chou and Talalay's statistical analyses (CalcuSyn software).
The International Classification of Headache Disorder provides explicit diagnostic criteria in order to minimise the diagnostic variability [1].
Three separate experiments were performed to minimise the biological variability (Zien et al, 2003).
To minimise the interobserver variability, scoring was performed by two independent investigators without the knowledge of the clinicopathological data.
Polyurethane foam was chosen to minimise the overall variability of bone substrate, as the purpose of this experiment was to compare the stability of different fixation methods.
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