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If this is the case, the minimally worthwhile treatment effect will be equivalent to 10% of the mean initial size.
The minimally worthwhile treatment effect is based on the assumption that the mean initial size of participants' pressure ulcers will be 100 cm.
If, however, the mean initial size of participants' pressure ulcers is not 100 cm, the absolute minimally worthwhile treatment effect will be adjusted post hoc to correspond with 10% of mean initial values.
This assumes an SD of 30 cm, loss to follow-up of 15%, correlation with a baseline of 0.6, an α of 0.05 and a minimally worthwhile treatment effect of 10 cm.
Similar(56)
An approach that is often preferred is to power the study to detect a minimally important difference (MID the magnitude of improvement for which patients would consider a course of treatment to be worthwhile.[ 3] In some instances, an MID estimate may be unavailable so a pilot study may be needed.
Minimally processed.
He was minimally conscious.
Minimally invasive tumor therapies.
Worthwhile conversations.
Definitely worthwhile.
Anything worthwhile happened here".
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