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Secondly, based on metabolic control analysis, it can be inferred that this minimization of changes in metabolite concentrations causes pathway fluxes to be minimally sensitive to temperature variations (see Additional file 4).
Numerical studies illustrate that a CZM employing the separation or strain based fatigue damage rate function is highly sensitive to phenomenological cohesive strength and stiffness parameters, whereas a CZM employing the SERR based damage rate function is minimally sensitive to the same static parameters.
The model economic outcomes were minimally sensitive to changes in vaccination coverage and PCV13 effectiveness.
This timing ensured that scans were maximally sensitive to the different types of linguistic representations and minimally sensitive to the onset of the visual cue.
Because this assay is conducted at stoichiometric concentrations of the protein and DNA, it is minimally sensitive to the enhanced protein binding at low cation concentrations where the rate of dissociation of the complex is low.
Indeed, the preliminary data showed that UV-C induced both hyperactivation of ERK and cell death in T98G and U251 cells, but this was not prevented by MEK inhibitors (data not shown), and X-ray-induced cell death of both glioma cell lines was also only minimally sensitive to ERK pathway inhibition.
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The average temperatures in the UAE were between 30 and 47 °C (maximum) and 17 and 27 °C (minimum) during the study period (June to December 2012).The Fitzpatrick scale assessed 84% of the participants between grade IV and V that is, between minimally sun sensitive to sun insensitive, burns minimally to rarely burns and always tans to moderate brown to tans well.
However deletion mutants of components of the Rpd3L complex (rxt2Δ, ume1Δ, pho23Δ, sap30Δ and sin3 Δ, dep1Δ) are minimally or moderately sensitive to CG-1521, indicathat that CG-1521 inhibits several HDACs.
It was formerly reported that a recG mutant was highly sensitive to EcoKI mediated DNA cleavage while a ruvABC mutant was minimally sensitive [7].
CYP450 2C19 was most sensitive to inhibition, showing 35% inhibition of activity at a concentration of 0.5 μg/mL of BV-9238 whereas CYP450 2E1, CYP450 2D6, and CYP450 2C9 activities were minimally sensitive.
A dry hand does not grip well and is minimally sensitive.
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minimally invasive to
minimally dangerous to
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com