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Instead of focusing on regular board "governance" (an activity I think is only minimally needed in good startups), I ask CEOs to focus on the most critical and pivotal risks, questions, and opportunities facing the company.
By the late 1980s only 1,500 km pipelines were under maintenance, half of what was minimally needed.
"And like I usually do," says Aronofsky, "I stuck to my independent craft and tried to figure out what I really, actually, minimally needed, and I did it".
Such partially edited mRNAs might be a consequence of T. brucei encoding thousands of different gRNAs, many more than minimally needed for the editing, many of which specify substantially overlapping regions.
These issues should be carefully considered to determine the sample size which is minimally needed to achieve reliable model estimates.
It was thus found that intraportally injected grafts minimally needed 2.10 β-cells/kg body weight in order to consistently induce glucose-regulated C-peptide release in C-peptide negative type 1 diabetiC-peptide negative
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Alternatively, what equipment would you minimally need, and how much would it cost?
But we need to be clear and careful about what minimally needs to be the case for LOTH to be true, and why.
If a transition "je 0" has occurred, for example, and we are looking at the base emission for the "e 0" state, we cannot account for the prior state with the simple conditional probabilities in the standard bare-bones HMM modeling, we minimally need, that is, state modeling at the dimer level or higher.
In order to obtain reliable results, a Delphi panel minimally needs to consist of 10 to 15 experts[ 10].
In the studies that were published, the polio immunogenicity of this product was not as good as a comparator vaccine, and it was clear from the data that the IPV dose would minimally need to be the same as the current vaccine and may need to be increased.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com