While Fiat has started exporting its Palio to India, its best seller here is the Uno, a 20-year-old Italian design, minimally modified for Brazil and retailing for just over $4,000.
No antisense efficiency was demonstrated for the minimally modified ODN when internalized with Superfect®.
To determine the minimally modified electronegative LDL (LDL−) and its autoantibodies in coronary syndromes.
Our method can generate a symmetric layout through minimally modifying the original input layout.
Minimally modified low density lipoprotein (mmLDL) is a well-known risk factor for cerebral vascular diseases and upregulation of endothelin type B (ETB) receptors plays key roles in the pathogenesis.
The aim of this study was to determine if the minimally modified LDL, obtained after the ingestion of three different diets, produce differential effects on the vascular cell adhesion molecule-1 (VCAM-1) and E-selectin expression in human umbilical endothelial cells (HUVECs).
In the perspective of reversing multidrug resistance through antisense strategy while avoiding non-antisense effects of all-phosphorothioate oligonucleotides which non-specifically bind to proteins, a minimally modified antisense phosphodiester oligodeoxyribonucleotide has been designed against mdr1, one of the multidrug resistance genes.
In addition, we leverage recent results on Cayley configuration spaces to show that the indecomposable systems – that are solved at the nodes of the optimal DR-plan by recombining solutions to child systems – can be minimally modified to become decomposable and have a small DR-plan, leading to efficient realization algorithms.
However, there are situations in which evidence or information may be minimally modified (such as by the use of pseudonyms) or generalized, in order to avoid identification of the source and to protect confidentiality and limit exposure of people to risks.
We hypothesized, that the HIP/PAP (the lactose-binding protein) should bind minimally modified 18F-labeled lactose analogues with high affinity, and that this "receptor-ligand" type of an imaging approach should allow for visualization of peritumoral infiltrated pancreatic tissue that 130-fold over-expresses the HIP/PAP protein, as compared to normal pancreatic tissue.
