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Reliability and validity testing was then performed and the minimally importance difference (MID) explored.
(AOM): anti-obesity medication; (TRIM-Weight): Treatment Related Impact Measure of Weight; (PRO): patient reported outcomes; (HRQoL): health related quality of life; (BMI): body mass index; (MID): minimally importance difference.
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Minimally important difference.
Smelt also established a between-group minimally important difference (MID) of -1.5 points [40].
In studies to find the minimally important difference, the ARR produced 20% larger differences in the medians than the NNT (25% versus 5%).
This was greater than the minimally important difference.
We calculated the minimally important difference in two ways.
The minimally important difference in consecutive PAQLQ scores is 0.5.
Conservatively, differences of ≥3 points were considered the minimally important difference in HRQL scores.
Minimally important difference (MID) values were estimated via anchor based method, while minimally detectable difference (MDC) figures were calculated by distribution based method.
The minimally important difference for the total score was calculated at 1.75.
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