However, the statistical significance of the difference between native and truncated actin in the case of TM1b9a is ambiguous, as the t-test generated p = 0.07, which minimally exceeds the threshold of significance.
Many of us know someone, or know someone who knows someone, who has managed to live a Woody Allen life in a sprawling West Side classic-six for monthly carrying costs that would seem only minimally to exceed the cable bill.
These effects exceeded the minimally important difference of 5 points [ 16] (Table 2).
The magnitude of the improvements also exceeded the minimally important difference reported for the SF-36[ 22].
All these differences exceeded the minimally clinically important difference (MCID) of between 0.02 and 0.03(Fig. 1).
Notably, the magnitude of the postmenopausal effect in diffuse SSc (−3.36 units, 95% CI −5.87, −0.85) exceeded the minimally important difference in the mRSS [ 19].
General health and vitality were significantly improved in both groups (mean (SD) change scores for PRT were 12.2(11.5) and 10.5(18.2), and for AT, 13.3(19.6) and 10.0(13.1), respectively) and exceeded the minimally important difference of 5 points.
Findings from our primary endpoint analysis of change from baseline in FEV1 after24 after 6 weeks of treatment demonstrated a statistically significant improvement with aclidinium versus placebo, and changes from baseline in trough FEV1 with aclidinium exceeded the proposed minimally important difference for this parameter (100 140 mL) (15, 16).
The scales are only two items each, their reliabilities all meet or exceeded the value of.50 regarded as minimally acceptance [ 16, 35].
However, because of the considerable within group variability of the clinical data in patients with lung cancer, to improve the power of our results, we decided to exceed the minimally required sample size by enrolling 20 additional subjects.
Spironolactone significantly improved quality of life with a between-group difference of 0.10 in the EQ-5D compared with placebo, a value that exceeds the minimally clinically important difference of 0.08.
