Sentence examples for minimally effective at from inspiring English sources

was minimally effective at reducing tumour growth in a MDA-MB-231 xenograft model, but acetylating EGCG and thus turning it into a pro-drug enhanced its efficacy (Landis-Piwowar et al, 2007).

The good fit of our model, absent predictors for the influence of interventions, suggests that interventions (including border closings) were minimally effective at stemming regional spread of Ebola virus infection during the period analyzed.

Due to the extreme divergence (< 20% identity) of PDC/PAS domain sequences, sequence similarity search methods such as Basic Local Alignment Search Tool BLASTT) [ 23, 54] or FASTA [ 55] are minimally effective at identifying PDC/PAS proteins.

In addition, Bluestone and colleagues (4) demonstrated that conventional polyclonal CD4+CD25+ Tregs were minimally effective at reversing type 1 diabetes in NOD mice, but purified antigen-specific CD4+CD25+ T-cells reversed type 1 diabetes in 60% of NOD mice.

While PM and CO concentrations were somewhat elevated in homes without chimneys as compared to rural homes with chimneys, we did not see a significant difference in these concentrations, indicating that locally constructed chimneys were minimally effective at reducing exposures to biomass smoke in our population.

After chloroquine therapy for the primary attack, relapse did not commence until levels of drug slipped below the minimally effective concentration at approximately day 35, and the relapse rate reached 50% by day 63.

And 528 (about 13percentt) were deemed minimally effective, placing them at risk for dismissal next year.

Similar to other drugs, the desired action of methadone requires that it must attain a certain in vivo concentration (the minimally effective concentration, MEC) at its site of action in order to provide a therapeutic effect.

It is plausible that effective disease-modifying interventions might be only minimally effective or even futile at the dementia stage; neuroprotection or favorable effects on the inciting amyloid dysregulation might be overwhelmed by extensive neuronal/synaptic degeneration and plaque pathology.

Cost per QALY for the 6 months' duration used in these analyses showed that values ranged from $39,805 for the minimally effective scenario with costs at 50% of original to a $58,114 for the highly effective scenario evaluated at 150% of original costs (Additional file 2).

Re-evaluating the need for a long-term corticosteroid therapy or using it at a minimally effective dose is warranted.