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These results demonstrate that ambient GABA concentration is an important determinant of the hypnotic and immobilizing actions of propofol and midazolam in mice, whereas manipulations of ambient GABA concentrations minimally alter cellular and behavioral responses to sevoflurane.
It is acknowledged that some of these factors do not or minimally alter pharmacokinetics of these agents if taken independently.
Previous work on disulfide stabilization of the gp120 core has identified multiple double-cysteine mutations that minimally alter the antigenic profile of gp120.
C15 was mutated to alanine and also to the more conservative serine to remove the thiol but minimally alter the polarity and size of the side chain.
According to our model predictions, experiments with both inhibition and overexpression of MKP3 should minimally alter the Raf-1-P amplithee if the in-vivo system is strongly sequestrated.
Given our observations of target-base coverage saturation at ≥ 20x threshold for 20 23 Gb aggregate user-quality data, we conclude that an extra 1.7-2.1 1.7-2.1sample would minimally alter the overall interpretation of tarGbted regions under evaluation (see Additional file 1: Figure S6).
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Unfortunately, another region's elements were inadvertently used to create the UK in-home release which minimally altered this scene in the film.
But five other works, the court said, were so minimally altered by Mr. Prince that they might not be considered fair use by a reasonable observer.
To do that, hundreds of people were recruited online to compare sets of before-and-after images and to determine the 1-to-5 scale, from minimally altered to starkly changed.
The first type of privacy, called output privacy, is that the data is minimally altered so that the mining result will not disclose certain privacy.
The similarities between these samples suggest that the sorption capacity of the kerogen was minimally altered during transport and deposition, and that humic substances were not co-deposited with the kerogen in the glacially-deposited sediments.
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CEO of Professional Science Editing for Scientists @ prosciediting.com