Sentence examples for minimal toxicity was from inspiring English sources
Maximum transfection activity with minimal toxicity was observed when the quaternary polyplex of pDNA/PEI/PAA/P8Am was prepared at a weight ratio of 1/1.5/3/5.
In a Phase I/II, clinical activity with minimal toxicity was observed at multiple dose levels in mutant BRAF tumors [9].
Minimal toxicity was observed at doses up to and including 8 mg/m.
A lower dose of 400 mg m−2 bolus + 2400 mg m−2 infusion which, like dG produces minimal toxicity, was chosen for the OxMdG combination.
Minimal toxicity was observed in patients with centrally located tumors, highlighting the potential benefit of protons for tumors with clinically challenging locations and larger size.
These experimental findings are supported by a clinical trial where encouraging activity with minimal toxicity was observed in patients with breast cancer [ 10].
Regimens with clinical benefit and minimal toxicity are urgently needed.
Finally, the development of methods to improve the early diagnosis of SCID along with designing prospective trials to evaluate the best approaches to curing these diseases with minimal toxicity are critical to improving outcomes for children with SCID.
Natural antipyretic remedies with minimal toxicity are therefore essential.
Thus, novel intravesical agents with proven efficacy and minimal toxicity are urgently required for the treatment of bladder cancer.
In this sense, potent autophagy agonists or inhibitors with minimal toxicity are promising candidates for developing effective anticancer drugs [ 12, 13].
