Sentence examples for minimal systemic toxicity from inspiring English sources

Bone-targeted radiation therapy is an attractive strategy for addressing bone disease with minimal systemic toxicity.

Intravesical administration is a well-established method to introduce pharmacological agents locally with minimal systemic toxicity that is unique to the urinary tract.

The toxicological data for chloroxylenol indicate lack of genotoxicity, no evidence of carcinogenicity, and minimal systemic toxicity.

The major advantage of this combined strategy is the ability to optimize local therapy, by maintaining an effective and sustained concentration of therapeutics in the brain with minimal systemic toxicity.

Furthermore, in children, bortezomib is associated with minimal systemic toxicity [24].

Additionally, these particles have been demonstrated to show minimal systemic toxicity [11,12].

In addition, the safety evaluation showed that CAR-modified lymphocytes have no or very minimal acute systemic toxicity.

Alternatively, cosmetic ingredients with a low dermal bioavailability might not need repeated dose data, as internal exposure will be minimal and systemic toxicity might not be an issue.

Due to the low mean maximum plasma concentrations there is minimal risk for systemic toxicity or drug-drug interactions.

In our rat liver tumour model (the CC531 colorectal carcinoma), isolated liver perfusion allows administration of higher doses of mitomycin C than hepatic artery infusion, while systemic toxicity remains minimal.

It treats the whole limb below the point of tourniquet isolation, can achieve 20 50 times higher concentrations of melphalan compared with systemic therapy, and can be performed with minimal locoregional toxicity and minimal systemic leakage [ 58].