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In combination with low proteinuria, possibly reflecting minimal systemic capillary leakage, a high BNP level was associated with a better outcome.
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Introduction Systemic Capillary Leak Syndrome (SCLS) is a rare disease characterized by recurrent life-threatening attacks of capillary hyper permeability in the presence of a monoclonal gammopathy (MG).
Introduction Systemic Capillary Leak Syndrome (SLCS) is a rare disease characterized by recurrent life-threatening attacks of capillary hyper permeability in the presence of a monoclonal gammopathy (MG).
Furthermore, in children, bortezomib is associated with minimal systemic toxicity [24].
Additionally, these particles have been demonstrated to show minimal systemic toxicity [11,12].
Bone-targeted radiation therapy is an attractive strategy for addressing bone disease with minimal systemic toxicity.
One key concept for reducing systemic side effects via pulmonary drug delivery is to select drug candidates with prolonged pulmonary efficacy and minimal systemic exposure [7, 9].
The toxicological data for chloroxylenol indicate lack of genotoxicity, no evidence of carcinogenicity, and minimal systemic toxicity.
In toxicological studies, after 1 month repeat application in minipigs minor dermal irritation and minimal systemic exposure were observed.
Our efforts resulted in the identification of compound 4a which significantly reduced food intake with minimal systemic exposure in rodents.
Two studies report minimal systemic absorption of orlistat.
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CEO of Professional Science Editing for Scientists @ prosciediting.com