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The Dmknδ5 protein displays the minimal sequence present in all the Dmknδ plus the amino acids encoded by the alternative exon 20.
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The minimal binding sequence, present in all interacting peptides, is 61GGAFPEIH68 (Figure 1B).
In addition, the SsrASTOP mutant that has a minimal tag sequence presented higher sensitivity to oxidative stress upon exposure to paraquat (Fig. 6).
Kidgell et al reported that genes located in the central regions of chromosomes (as is pfserca) usually present minimal sequence diversity [43].
We have used the cyclin binding motif (CBM) present in the tumor suppressor proteins p21WAF1 and p27KIP1 as a template to optimize the minimal sequence necessary for CDK2/CA inhibition.
The present manuscript extends our de novo peptide design approach to the synthesis and evaluation of a new generation of reversed-phase HPLC peptide standards with the same composition and minimal sequence variation (SCMSV).
Minimal sequence requirements for binding were first established using both crystallography and peptide spot synthesis.
The 129 sequences that remained had a minimal sequence similarity of ~30% and a minimal sequence coverage of ~50% as compared to hDBC1, complying with previous studies [ 42].
This analysis showed that detection of a microbe with a large genome (which theoretically contains a large number of virtual tags) can be achieved with minimal sequencing when such microbes are present in virtually all host cells analyzed.
After the Clean Query (2) step, the query becomes A→B→C, since Y is not present in the list of minimal sequences.
The next step, Clean Query (2), is responsible for eliminating from this query the tasks that are not present in the list of minimal sequences, i.e., it eliminates tasks that do not appear in any path pattern.
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