Sentence examples for minimal sensitization from inspiring English sources
We observed that TNFα or IFN-γ alone exhibits minimal sensitization effects, but effectively sensitized metastatic colon carcinoma cells to TRAIL-induced apoptosis when used in combination.
We observed that TNFα alone exerted minimal sensitization effect on metastatic colon carcinoma cells.
CD44v7-10 RNAinin PC-3M cells caused marked sensitization to Docetaxel; the two CD44s re-expression approaches caused minimal sensitization.
Four of the 6 primary colon carcinoma cell lines (SW480, HT29, HCT116 and LS174T) are highly sensitive to FasL-induced apoptosis, and LCL85 exhibited minimal or no sensitization effects on these 4 sensitive cell lines.
However, LCL85 also only exhibited minimal or no sensitization effects on these 2 cell lines.
In contrast, there was minimal or no sensitization of the LN-18 cells to TMZ after transfection with the control scL-vec, again demonstrating that the response in these resistant cell lines is due to the presence of exogenous wtp53 and not nonspecific cytotoxicity.
This sensitization occurred with minimal effect on DR4 or DR5 mRNA expression and little if any change in cell surface levels of these receptors (Supplementary Figure S3).
Importantly, after central sensitization has been established only minimal nociceptive input is required for the maintenance of the chronic pain state.
For instance, a subgroup of individuals with knee osteoarthritis (those with higher pain intensity but minimal radiographic change in the knee) exhibiting strong sensitization has been identified [10].
sensitized for 12 hours expressed minimal mRNA transcripts for p40, IL-6, IL-1β, and TGFβ, whereas CD11c+ DCs from inguinal LN after s.c. sensitization expressed significant increased mRNA transcripts for p40, IL-1β, IL-6, but not TGFβ.
This is likely to be due to the lack of endogenous SP release, which would result in the level of NMDA activation being minimal (due to the lack of SP-mediated NMDA receptor sensitization as explained previously).
