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This was not the case for GO-FORWARD, as minimal progression was observed in all patients regardless of treatment.
At 52 weeks, the majority of patients exhibited no or minimal progression of structural damage (figure 3C).
At week 104, the majority of patients demonstrated minimal progression of radiographic structural damage, with differences favouring the add-on group (table 2, figure 3A).
There was very minimal progression of radiological lucency from early postoperative period to the most recent follow-up in individual zones around the components.
The effect of golimumab on bone erosions could not be determined by semi-quantitative scoring in these RA patients with minimal progression of bone erosions.
This minimal progression precludes placebo-controlled trials and necessitates treatment groups of several hundred patients to ensure sufficient power to detect even modest treatment group differences.
Similar(51)
After minimal radiological progression, the patient agreed to combined chemotherapy.
ACPA-negative patients had minimal radiological progression irrespective of treatment.
Both strategies improved quality of life similarly and resulted in minimal erosive progression.
The difference in minimal radiological progression can be interpreted in several ways.
However, short lived flares and minimal radiographic progression were more frequent in the dose reduction group.
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