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Although the lower levels of patient acuity and minimal organ dysfunction raise the question whether these results can be transposed to other groups of critically ill patients, we assert that acute physiological effects of hemodilution are likely to be comparable across various patient groups, although the magnitude of the effect may be variable.
Similar(59)
ARDS: acute respiratory distress syndrome; CFU: colony forming unit; COPD: chronic obstructive pulmonary disease; HIV: human immunodeficiency virus; ICU: Intensive Care Unit; LODS: Logistic Organ Dysfunction System; MIC: minimal inhibitory concentration; NYHA: New York Heart Association; SAPS: Simplified Acute Physiology Score; S.pneumoniae: Streptococcus pneumonia.
Given this risk of organ dysfunction [ 8, 9], the reported minimal treatment effects and potential for harm with interventions for established organ failure [ 10, 11], an alternative approach is to evaluate drugs with pleotropic effects to prevent progressive organ dysfunction in a pre-ICU population of patients with infection.
Sequential organ dysfunction assessment.
multiple organ dysfunction syndrome.
paediatric logistic organ dysfunction.
pediatric logistic organ dysfunction.
Multi Organ Dysfunction Score.
Predisposition, infection, response, and organ dysfunction.
All had multiple organ dysfunction at presentation.
Despite pulmonary failure, organ dysfunction was moderate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com