The minimal necessary representative sample size was calculated to 3000 subjects to ensure statistical power[ 8] for examining the various cardiovascular risk factors of interest, i.e. to ensure a statistical precision of at least 2% for the estimation of the prevalence of the risk factors at the 95% confidence level.
Hence, detection of minimal necessary Ag+ concentration in DLC-Ti samples was evaluated in a further testing series with low concentrations of Ag within the DLC coating (Ag PVP = 1 10 and 1 20).
For example, to detect the true difference in 1-month survival with minimal neurologic impairment (17.5% versus 24.4%), the necessary sample size was estimated to be 1,321 on the basis of a two-sided α value of 0.05 and a β error of 0.20 [ 35].
It is very difficult to establish exactly the minimal necessary dose for any given examination [1].
Time-lapse imaging (2 hours) was performed with minimal necessary laser power.
Prior to beginning the experiment, the minimal sample size necessary to reject the null hypothesis can be calculated at the desired confidence interval, as well as the number of expected cases of each genotype, assuming Mendelian inheritance.
The minimal required sample size was calculated to be 49.
Minimal sample manipulation is required, no derivatization is necessary, and information useful for identification of novel metabolites is obtained.
A power analysis revealed that if the correlation between male length and offspring viability were at the upper limit of our calculated confidence interval, a minimal sample size of 88 males and more than 21,300 experimentally fertilized eggs would be necessary to demonstrate the effect at alpha ≤ 0.05 with our experimental methods and with a statistical power of at least 80%.
Probably, the measured activation of caspase-3 was not sufficient to exceed the minimal threshold necessary to trigger apoptosis; (iii) to highlight that in about 60 70% of CLL samples studied, quercetin per se induces apoptosis, as indicated by decreased cell viability and increased caspase-3 activity and Annexin V positivity (CLL-55, 44, and 11).
