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During echocardiographical examination in four dogs minimal mitral valve regurgitation was found with a reflux smaller than 20% of the left atrium using colour Doppler, and with a broken profile in early systole using continuous-wave Doppler.
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In our technique, the transmural mattress sutures incorporating both ventriculotomy patches require minimal bites toward the mitral valve annulus and the posteromedial papillary muscle, thereby preserving the mitral valve function.
LA maximal volume (Vmax) was recorded at the onset of mitral opening, LA minimal volume (Vmin) was recorded at the onset of mitral closure and LA presystolic volume (Vp) was recorded at the beginning of the atrial systole (p wave on ECG).
The transmural mattress sutures incorporating ventriculotomy patches required minimal bites toward the posteromedial papillary muscle and mitral annulus, thereby preserving the mitral valve function.
Using in vitro models, the mechanics as well as surgical techniques for mitral valves (MV) and MV devices can be studied in a more controlled environment with minimal monetary investment and risk.
Another manifestation of myocardial relaxation, the ratio of early to late mitral annular velocity, was increased with G-1 treatment in the HS group while the GPER agonist had minimal effects in NS-fed rats (Figure 5).
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