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In conclusion, the microneedle arrays used in this study are able to overcome the barrier function of the skin in human volunteers, are painless and cause only minimal irritation.
For example, an activity such as shopping may be considered a utilitarian shopping concerned with efficiently purchasing products to achieve a goal of minimal irritation, or a hedonic shopping which emphasizes the pleasure and enjoyment that result from the shopping experience (of course, a single activity may have some of both qualities) [18].
Less than eight minutes later, hair will wipe off with minimal irritation and sans the off-putting smells other creams can emit.
Sevoflurane mask anesthesia causes minimal irritation due to preserved spontaneous ventilation and lower airway reflex stimulation.
In sharp contrast to results obtained from individual subjects, we found that the minimal irritation results in stereotypic vascular reaction which could also be used to evaluate the reactivity of local compensatory reactions.
In contrast to the results obtained from individual subjects, the minimal irritation (such as gentle scratching) results in stereotypic vascular reaction (see Media 2 and 4) which can be used to evaluate the reactivity of local compensatory reactions.
Similar(53)
We demonstrate that the system is capable to detect the minimal irritations of the body such as gentle scratching of the skin by own finger.
Most dermal irritation studies using rabbits classified dimethicone as a minimal irritant.
Minimal ocular irritation was seen with one formulation containing lipophilic extract of C officinal and no irritation with other extracts [43, 44].
The presence of the appliance is well tolerated by patients and resulted in minimal tissue irritation and no gingival overgrowth.
It is designed to produce a continuous active intrusion force with infrequent need for reactivation, be easy to install, reactivate and remove, and be hygienic with minimal tissue irritation.
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