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The low but detectable thrombin generation (352 ± 55 nM) measured in plasma from an IVS6 + 1G > T homozygote was consistent with a minimal initiation of the enzymatic cascade.
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Among the Khamba (khams pa) of eastern Tibet, for example, men with minimal monastic initiation (lung) organized themselves as a military or police force to protect monastic territory and the unarmed higher-initiated clergy.
Tumors were observed within the first week for the untreated KHOS group, whereas the amiloride-treated group showed minimal tumor initiation and progression (Fig. 3C).
Because IRESs operate with reduced complexity and constitute minimal systems of initiation, comparison with canonical initiation may allow common mechanistic principles of the ribosome to be delineated.
We present detailed protocols for the purification of all essential protein components of the minimal eukaryotic transcription initiation complex.
However, peaks in the replication timing profiles must contain at least one origin, so that a minimal number of initiation events at different time points throughout S phase could be extracted from the replication profiles.
Peaks in the profile once again must contain at least one origin, so that a minimal number of initiation events at different time points through S phase could be extracted from the replication profile by counting the number of peaks using the algorithm described above.
Our studies provide a new set of tools and previously not accessible data to gain new understanding of the molecular basis of MOMP, suggesting that the minimal requirement for initiation of MOMP requires Bax, a phospholipid bilayer and Bid BH3 peptide.
Translation of the hepatitis C virus (HCV) genomic RNA initiates from an internal ribosome entry site (IRES) in its 5′ untranslated region and requires a minimal subset of translation initiation factors to occur, namely eukaryotic initiation factor (eIF) 2 and eIF3.
A minimal model of stochastic initiation modulated by accumulation of a recyclable, limiting replication-fork factor and fork-promoted initiation of new origins, quantitatively describes the observed profiles.
A previously proposed minimal model of stochastic initiation modulated by accumulation of a recyclable, limiting replication-fork factor and fork-promoted initiation of new origins, quantitatively described the observed profiles without requiring new implementations.
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