Sentence examples for minimal inhibitory effect from inspiring English sources

Rolipram is the prototypal PDE4 selective inhibitor, first described more than three decades ago [21], and it is generally admitted that at the dosage used in this study, rolipram has minimal inhibitory effect on other PDE families and does not interfere with unrelated signalling pathways [11].

The time-dependent evolution of tumor volume in mice inoculated with CNE-2 and C666-1 cells (Figure 5A and B) indicated that treatment with mc-oriP-IFNγ had minimal inhibitory effect on EBV-negative CNE-2 tumors compared with the control p2ΦC31 group (Figure 5A).

SB203589 (15 μ M) had minimal inhibitory effect on MMP-1 production, and actually enhanced proliferation in response to EGF.

As a control, V-E235A, which is deficient in binding to MDA5 [ 53] (as detailed in Additional file 5), showed a minimal inhibitory effect, as expected.

In the wt-MCF7 cells nilotinib had no effect on ER/ERE-mediated transactivation in the absence of E2 and a slight, but minimal inhibitory effect in the presence of E2.

The dose of CQ was set at 80 μM because it was the dose that mostly induced AVOs formation, the marker of autophagy, with minimal inhibitory effect on HT-29 cells.

In immunotherapy of the MCA205 sarcoma, administration of the neutralizing anti-IL-12 mAb nearly completely blocked the adjuvant effect of IL-12, but had minimal inhibitory effects on anti-OX-40R mAb.

Generally, DMSO was determined as the most activity enhancing solvent presumably allowing the PO to retain its active confirmation [Tominaga et al. 2004], whereas the protic solvents ethanol and methanol gave minimal inhibitory effects on activity.

In addition, whereas the ΔRF and ΔCys mutants showed growth suppressive effects that were almost identical to the wild-type CHFR, the ΔFHA protein had minimal inhibitory effects upon cell proliferation (Fig. 2A).

However, ACBP showed minimal inhibitory effects on normal cells that we tested, such as human skin fibroblast HS-68 cells and rabbit bone marrow mesenchymal stem cells (Su X, unpublished data).

There was lower ROS produced at the more selective dose of 3 µM that had a minimal growth inhibitory effect on normal keratinocytes.